/*Dosing page Css*/
/*********Dosing page Desktop Css starts here**************/

/*********Banner Css starts here**************/
.dosing-banner-main {
    background-image: url(/content/dam/intelligentcontent/brands/breztri-hcp/us/en/images/phase2/desktop/safety/safety_bg.jpg);
    background-repeat: no-repeat;
    background-size: cover;
    background-position: right center;
    min-height: 230px;
}

/*  US-106667 - BREZTRI HCP Website January 2026 Update Style start here */

.fixed-dose-main {
    position: relative
}

/* .fixed-dose-main::before {
    content: '';
    position: absolute;
    left: 0;
    top: 0;
    background: linear-gradient(-55.9deg, rgba(255, 255, 255, 0.8) 57.23%, #c5f1f2 117.01%);
    width: 50%;
    height: 80%;
    z-index: -1;
}

.fixed-dose-main::after {
    content: '';
    position: absolute;
    right: 0;
    top: 0;
    background: linear-gradient(55.9deg, rgba(255, 255, 255, 0.8) 57.23%, #c5f1f2 117.01%);
    width: 50%;
    height: 80%;
    z-index: -1;
}
*/
/*  US-106667 - BREZTRI HCP Website January 2026 Update Style end here */


 
.dosing-banner-main::after {
    content: '';
    position: absolute;
    left: 0;
    bottom: 0;
    width: 100%;
    height: 10px;
    background: linear-gradient(90deg, rgba(195, 137, 0, 1) 0%, rgba(240, 178, 36, 1) 50%);
}

.dosing-banner {
    padding: 0;
}

.dosing-banner-inner {
    padding:90px 0 30px 0;
}

.dosing-banner-content {
    padding: 0; 
}

.dosing-banner-main a {
    padding: 0 0 4px 0;
    margin: 0 0 14px 0;
    border: none;
    border-bottom: 2px solid #2CD5C4;
    border-radius: 0;
    font-size: 18px;
    line-height: 24px; 
    color: #FFFFFF;
    text-transform: capitalize;
    display: inline-block;  font-family: 'Avenir-Heavy'; font-weight: 800;
}

.dosing-banner-content h1 {
    font-size: 40px;
    line-height: 44px;
    font-weight: 800;
    margin: 0 0 12px 0;
    font-family: 'Avenir-Black';
    color: #FFF;
}

.dosing-banner-content p {
    font-family: 'Avenir-Book';
    font-size: 16px;
    line-height: 24px;
    color: #fff;
}

.twice-daily sup {
    line-height: 100%;
    font-size: 58%;
}

/*********Banner Css ends here**************/
/*********fixed-dose Css starts here**************/

.fixed-dose-main {
    padding: 32px 0 34px 0;
}

.fixed-dose-inner {
    max-width: 746px;
    margin: 0 auto;
}

.twice-daily {
    padding: 0px 0 2px 24px;
    position: relative;
    margin: 0 0 24px 0;
}

.twice-daily::before {
    content: '';
    position: absolute;
    left: 0;
    top: 0;
    background: #F0B323;
    width: 3px;
    height: 100%;
    border-radius: 16px;
}

.twice-daily p {
    font-family: 'Avenir-Book';
    font-size: 24px;
    line-height: 32px;
    color: #121312;
}

.inhaler-inner {
    display: flex;
    gap: 60px;
    padding: 0 0 0 14px;
}

.inhaler-inner figure {
    margin: 0;
    max-width: 319px;
}

.inhaler-inner p {
    color: #121312;
    font-family: 'Avenir-Medium';
    font-size: 32px;
    font-weight: 800;
    line-height: 38px;
    margin-bottom: 28px;
    letter-spacing: 0.6px;
}

.inhaler-left {
    max-width: 209px;
}

/*********fixed-dose Css ends here**************/
/*********copd treatment Css starts here**************/
.copd-treat-main { 
    max-width: 990px;
    margin: 0 auto;
    padding: 32px 48px;
    border-radius: 16px;
    background: #FFFFFF;
    margin-bottom: 50px;
    box-shadow: 0px 4px 25px 0px #00000017; 
    margin-top: 20px;
}

.copd-action h3 {
    border-top: 2px solid #2CD5C4;
    padding-top: 20px;
    color: #121312;
    font-family: 'Avenir-Medium';
    font-size: 25px;
    font-weight: 800;
    line-height: 32px;
    margin-top: 20px;
}
.copd-action h3 sup { font-family: 'Avenir-Book'; font-weight: normal;}
.copd-action b {
    font-size: 18px;
    color: #121312;
}

.copd-action p {
    font-family: 'Avenir-Book';
    font-size: 18px;
    line-height: 24px;
    color: #121312;
    padding-bottom: 10px;
}

.copd-action .action-p {
    padding-top: 10px;
    font-size: 16px;
    line-height: 24px;
} 

.copd-mcg {
    width: calc(52% - 20px);
}

.copd-treat-inner {
    display: flex;
    align-items: stretch;
    gap: 40px;
    max-width: 1200px;
}

 

.copd-mcg {
    max-width: 440px;
    padding: 0 0 0 30px;
    position: relative;
    align-items: center;
    display: flex;
}

.dose-copd p {
    color: #121312;
    font-family: 'Avenir-Medium';
    font-size: 24px;
    font-weight: 800;
    line-height: 32px;
}
.dose-copd p sup { font-family: 'Avenir-Book'; font-weight: normal; }
.copd-mcg p {
    font-family: 'Avenir-Book';
    font-size: 16px;
    line-height: 24px;
    color: #121312;
}

.copd-mcg::before {
    content: '';
    position: absolute;
    left: 0;
    top: 0;
    background: #B4B8B2;
    width: 3px;
    height: 100%;
    border-radius: 16px;
}

 

/*********copd treatment Css ends here**************/
/*********patients-video Css starts here**************/
#dose-patients {
    max-width: 990px;
    margin: 0 auto 32px;
    display: flex;
}

#dose-patients>.aem-Grid {
    display: flex;
    justify-content: space-between;
}

#patients-know {
    max-width: 584px;
    display: flex;
}

#patients-video {
    max-width: 453px;
    display: flex;
    margin: 0px 0 0 60px;
}

.patients-know p {
    color: #121312;
    font-family: 'Avenir-Medium';
    font-size: 32px;
    font-weight: 800;
    line-height: 38px;
    padding-bottom: 32px;
}

.patients-lists ul li {
    padding: 8px 0px 5px 0px;
    position: relative;
    margin: 0;
}

.patients-lists ul li span {
    font-family: 'Avenir-Medium';
    font-weight: 800;
    width: 64px;
    height: 64px;
    border-radius: 50%;
    background: #F5F5F5;
    color: #227870;
    display: inline-flex;
    justify-content: center;
    align-items: center;
    font-size: 24px;
}

.patients-lists ul li p {
    font-family: 'Avenir-Book';
    font-size: 16.5px;
    line-height: 24px;
    color: #121312;
    display: flex;
    flex-wrap: wrap;
    gap: 25px;
    align-items: center;
}

.patients-lists ul li p b {
    font-weight: normal;
    width: calc(100% - 89px);
}

.patients-lists ul li:nth-child(1) p b {
    max-width: 387px
}

.patients-lists ul li:nth-child(2) p b {
    max-width: 387px
}

.video-links-main {
    margin: 0 auto;
    max-width: 320px;
    display: flex;
    justify-content: center;
}

.video-links-main p {
    color: #227870;
    font-family: 'Avenir-Heavy';
    text-decoration: underline;
    font-size: 16px;
    font-weight: 800;
    line-height: 20px;
}

.video-links-main p a {
    color: #227870;
}

a.dose-link {
    max-width: 24px;
}

.video-links-main a:hover {
    color: #2B978D;
}

.video-links-main a:hover span {
    text-decoration: underline;
}

#patients-video .cmp-video__thumbnail {
    height: auto;
}

#patients-video .cmp-video__video {
    height: 304px;
}

#patients-video .cmp-video__player,
.cmp-video__content {
    padding: 0;

}

/****Video starts here****/
#dosing-page .dosing-video-block {
    max-width: 453px;
    padding: 0 0px 0 0px;
}

#dosing-page .dosing-video-view figure {
    margin: 0;
}

#dosing-page .dosing-video-view figure>a {
    display: inline-block;
    position: relative;
}

#dosing-page .dosing-video-view figure>a>img {
    margin: 0;
}

#dosing-page .dosing-video-view figure>a span.play {
    display: block;
    position: absolute;
    left: 0;
    right: 0;
    margin: 0 auto;
    text-align: center;
    top: 50%;
    transform: translateY(-50%);
    -moz-transform: translateY(-50%);
    -ms-transform: translateY(-50%);
    -o-transform: translateY(-50%);
    -webkit-transform: translateY(-50%);
}

#dosing-page .dosing-video-view figure>a span.play {
    width: 72px;
    height: 72px;
    border-radius: 100%;
    background-image: url(/content/dam/intelligentcontent/brands/breztri-hcp/us/en/images/global/icons/Global_Video_Screen_Play.png);
    background-repeat: no-repeat;
    background-size: cover;
}

#dosing-page .dosing-video-view figure>a span.play:hover {
    width: 72px;
    height: 72px;
    border-radius: 100%;
    background-image: url(/content/dam/intelligentcontent/brands/breztri-hcp/us/en/images/global/icons/Global_Video_Screen_Play_hover.png);
    background-repeat: no-repeat;
    background-size: cover;
}

#dosing-page .dosing-video-main {
    display: flex;
}

#dosing-page .dosing-video-list {
    width: 100%;
    margin: 0 0 20px 0;
}

#dosing-page .dosing-video-content {
    padding: 10px 0 5px 0;
}

#dosing-page .dosing-video-content h5 {
    font-family: 'Avenir-Medium';
    font-size: 18px;
    line-height: 24px;
    font-weight: 800;
    color: #121312;
}

/****Video ends here****/
/*********patients-video Css ends here**************/
/*********copd chronic Css starts here**************/
.copd-chronic-inner { 
    background: #FFFFFF;
    display: flex;
    max-width: 990px; 
    justify-content: center;
    align-items: center;
    margin: 0 auto; 
}
.dose-copd-chronic { padding:5px 0 10px 0;}
.dose-copd-chronic p {
    font-family: 'Avenir-Book';
    font-size: 14px;
    line-height: 20px;
    color: #373A36; padding-right: 60px;
}

/*********copd chronic Css ends here**************/
/*********Sample CTA button Css starts here************/
#dosing-page .sample-button a {
    padding: 20px 35px;
    border-radius: 48px;
}

#dosing-page .sample-button a {
    border: 3px solid #FEE2A0;
}

#dosing-page .sample .sample-button:first-child img {
    width: 24px;
}

#dosing-page .sample .sample-button:last-child img {
    width: 27px;
}


/* #Breztri janauvary  start*/

/* #dosing-page .sample .sample-button:last-child  */

#dosing-page .sample .sample-button:last-child:hover img {
    content: url("/content/dam/intelligentcontent/brands/breztri-hcp/us/en/images/phase1/global/vector.svg");
    width: 10px;
}

#dosing-page .sample-button2-order a span::after {
    top: 3px;
}

/* end */

/*  
#dosing-page .sample .sample-button:first-child span {
    padding: 0 10px 0 30px;
}

#dosing-page .sample-button2 a {
    background: #373A36;
    border: 3px solid #2CD5C4;
}

#dosing-page .sample-button a:hover {
    background: #FEE2A0;
    border: #F5CC6C 3px solid;
    box-shadow: 0 0 0 3px rgb(241, 229, 200);

}

#dosing-page .sample-button2 a:hover {
    background: #FFFFFF;
    border: #2CD5C4 3px solid;
    color: #121312;
    box-shadow: 0 0 0 3px rgb(214, 238, 245, 1);
    padding: 20px 35px;
}

#dosing-page .sample-button {
    width: initial
}

#dosing-page .sample-text span {
    display: none;
}

#dosing-page .sample {
    padding: 64px 0 64px 0;
    justify-content: center;
    gap: 30px;
}

#dosing-page .sample-view span {
    font-family: 'Avenir-Black';
    font-size: 20px;
    line-height: 26px;
}

#dosing-page .sample-view {
    display: flex;
    align-items: center;
    gap: 20px;
}

#dosing-page .reference-content sup {
    position: relative;
    top: 1.3px
}

#dosing-page .sample-button a::after {
    display: none
}

/*********Sample CTA button Css ends here**************/


#dosing-page .not-actual {
    font-size: 16px;
    margin-left: -107px;
    margin-top: -41px;
    color: #121312;
    font-family: 'Avenir-Book', sans-serif;
    font-weight: 55;
}

/*********Dosing page Desktop Css ends here**************/

.dosing-twice { padding:60px 0 0 0; max-width: 993px; margin: 0 auto; }
.dosing-twice-inner { padding: 0;}
.dosing-twice-inner > p { padding: 0; font-family: 'Gotham-Book'; font-size: 17px;
    line-height: 24px; color: #121312; text-align: center; }
.dosing-twice-inner h2 { 
    font-family: 'Avenir-Black';
    font-size: 39px;
    line-height: 44px;
    color: #121312; 
     font-weight: 900;
    text-align: center;
    text-transform: uppercase;
    padding: 0 0 30px 0; 
}
.dosing-twice-table { padding:0;  }
.dosing-twice-table figure { margin: 0; }
.dosing-twice-table figure img { margin: 0 auto; }
.patients-video-head { padding: 0;}
.patients-video-head h3 {
    font-family: 'Avenir-Black';
    font-size: 39px;
    line-height: 44px;
    color: #373A36;
    text-align: center;
    text-transform: uppercase; padding: 0 0 50px 0;
}

 
 

@media screen and (max-width: 1200px) {
    #dosing-page .dosing-video-main {
        padding: 0 15px 0 15px;
    }

    .copd-chronic-inner {
        max-width: 1080px;
        margin: 0 auto;
    }
}

/*********Dosing page Mobile Css starts here**************/

@media screen and (max-width: 991px) {

    /*********Banner Css starts here**************/
    .dosing-banner-main {
        background-image: url(/content/dam/intelligentcontent/brands/breztri-hcp/us/en/images/phase2/mobile/safety/safety-mob-banner.png);
        background-size: cover;
        background-position: 100% 26%;
        min-height: 220px;
    }

    /*  US-106667 - BREZTRI HCP Website January 2026 Update Style starts here */
    .fixed-dose-inner-mobile::before {
        content: '';
        position: absolute;
        left: 0;
        top: 0;
        background: linear-gradient(-85deg, rgba(255, 255, 255, 0.8) 66.75%, #c5f1f2 113.99%);
        width: 50%;
        height: 90%;
        z-index: -1;
    }

    .fixed-dose-inner-mobile::after {
        content: '';
        position: absolute;
        right: 0;
        top: 0;
        background: linear-gradient(85deg, rgba(255, 255, 255, 0.8) 66.75%, #c5f1f2 113.99%);
        width: 50%;
        height: 90%;
        z-index: -1;
    }



    /*  US-106667 - BREZTRI HCP Website January 2026 Update Style end here */

    .dosing-banner-inner {
        padding: 73px 0 20px 5px;
    }

    .dosing-banner-content a {
        margin: 0 0 14px 0;
    }

    .dosing-banner-content h1 {
        font-size: 29px;
        line-height: 33px;
        margin: 0 0 12px 0;
    }

    .dosing-banner-content p {
        max-width: 231px;
        font-size: 16px;
        line-height: 24px;
    }

    

    /*********Banner Css ends here**************/
    /*********fixed-dose Css starts here**************/
    .fixed-dose-main-mobile {
        padding: 24px 0 44px 0;
    }

    .fixed-dose-main-mobile .fixed-dose-inner-mobile {
        max-width: 100%;
        margin: 0 auto;
    }

    .fixed-dose-main-mobile .inhaler-main-mobile {
        padding: 0 0 22px 15px;
        text-align: center;
    }

    .fixed-dose-main-mobile .twice-daily-mobile {
        padding: 0px 0 0px 16px;
        position: relative;
        margin: 0 0 16px 16px;
        text-align: left;
    }

    .fixed-dose-main-mobile .twice-daily-mobile::before {
        content: '';
        position: absolute;
        left: -6px;
        top: 0;
        background: #F0B323;
        width: 3px;
        height: 100%;
        border-radius: 16px;
    }

    .fixed-dose-main-mobile .twice-daily-mobile p {
        font-size: 20px;
        line-height: 26px;
        font-family: 'Avenir-Book';
        color: #121312;
    }

    .fixed-dose-main-mobile .inhaler-right-mobile {
        width: 100%;
        text-align: center;
        padding: 10px 0 0;
    }

    .fixed-dose-main-mobile .inhaler-right-mobile figure {
        margin: 0 0 20px 0;
    }

    .fixed-dose-main-mobile .inhaler-daily-mobile p {
        color: #121312;
        font-family: 'Avenir-Medium';
        font-size: 24px;
        font-weight: 800;
        line-height: normal;
    }

    .fixed-dose-main-mobile .inhaler-dose-mobile-inner figure {
        margin: 0;
    }

    .fixed-dose-main-mobile .inhaler-dose-mobile {
        padding: 0 15px;
    }

    .fixed-dose-main-mobile .inhaler-dose-mobile-inner {
        max-width: 319px;
        margin: 0 auto;
    }

    /*********fixed-dose Css ends here**************/
    /*********copd treatment Css starts here*******/
    .copd-treat-inner {
        padding: 20px 24px 0px 24px;
        gap: 0;
    }

    .copd-mcg p {
        margin: 16px 0 0;
    }

    .dose-copd,
    .copd-mcg {
        width: 100%;
    } 

    .copd-mcg::before {
        display: none;
    }

    .copd-mcg {
        padding: 0;
    }

    .copd-treat-main {
        padding: 0 0 20px 0;
    }

    .copd-treat-inner {
        flex-direction: column;
        align-items: flex-start;
    }
 

    .copd-mcg {
        max-width: 100%;
    }

    /*********copd treatment Css ends here*******/
    /*********patients-video Css starts here**************/
    #dose-patients>.aem-Grid {
        flex-direction: column;
    }

    #patients-know {
        margin: 0 auto;
    }

    .patients-know {
        max-width: 585px;
        margin: auto;
        text-align: center;
    }

    .patients-know p {
        padding-bottom: 0px;
        font-size: 24px;
        line-height: normal;
    }

    #patients-video {
        margin: 32px 15px 0 15px;
        margin: 0 auto;
    }

    .patients-lists ul li {
        margin-bottom: 15px;
        padding: 0;
    }

    .video-links-main {
        margin: 10px auto 0;
        justify-content: center;
        max-width: 320px;
    }

    .patients-lists {
        width: 100%;
    }

    .patients-lists ul li.dose-twice {
        /*padding: 8px 0px 8px 0px;*/
        position: relative;
    }

    #dosing-page .dosing-video-list {
        margin: 0 0 0px 0;
    }

    /****Video start here****/
    #dosing-page .dosing-video-block {
        padding:10px 15px 0 15px;
        max-width: 585px;
    }

    #patients-video {
        max-width: 585px
    }

    #dosing-page .dosing-video-main {
        padding: 0;
    }

    #dosing-page .dosing-video-view figure>a>img {
        width: 584px;
    }

    /****Video ends here****/
    /*********patients-video Css ends here**************/
    /*********copd-chronic Css starts here**************/
    
    .dose-copd-chronic p { font-size: 12px; line-height: 14px; padding-right: 10px;}
    #dose-patients { margin: 0 auto 15px;}
    /*********copd-chronic Css ends here**************/
    /*********Sample CTA button Css starts here************/

    #dosing-page .sample {
        padding: 48px 0 72px 0;
    }

    #dosing-page .sample-button {
        text-align: center;
    }

    #dosing-page .sample-button a {
        display: inline-block;
    }

    .copd-action {
        padding: 0px 24px 0px 24px;
    }

    #dosing-page .sample-button2-order a span::after {
        top: 50%;
        transform: translateY(-50%);
        -webkit-transform: translateY(-50%);
        -moz-transform: translateY(-50%);
        -ms-transform: translateY(-50%);
        -o-transform: translateY(-50%);
    }

    #dosing-page .sample-button2-order a {
        padding: 17px 31px;
    }

    /*********Sample CTA button Css ends here**************/

    /* //19022026// */
    #dosing-page .not-actual {
        font-size: 12px;
        margin-left: 0px;
        padding-left: 160px;
        padding-bottom: 20px;
        margin-right: 0;
        margin-top: -41px;
    }
     .dosing-banner-content {
        max-width:320px;
    }

    .dosing-twice { padding: 18px 0 0 0; }
.dosing-twice-inner h2 { font-size: 26px;  line-height: 30px; padding: 0 0 15px 0; text-align: left;}
.dosing-twice-inne > p  { font-size: 17px;  line-height: 24px; text-align: left; padding: 0 0 30px 0; }
.dosing-twice-table p { font-family: 'Gotham-Book'; font-size: 12px;
        line-height: 16px; color: #121312; padding:0 0 0 40px; }
.dose-copd p { font-size: 23px; text-align: center;}
.copd-action h3 { font-size: 23px; line-height: 26px;}
.dosing-twice-table { margin-bottom: 14px; }
.copd-action p { font-size: 16px; line-height: 24px;}
.copd-action b  { font-size: 16px; line-height: 24px;}
.patients-video-head h3 { font-size: 26px; line-height: 30px; padding: 0 0 25px 0;}
.patients-video-head { padding: 30px 0 0 0;}
.dose-copd-chronic { padding: 0; }
 .dosing-twice-inner > p { padding: 0 0 20px 0; text-align: left;  } 
 .bronchospasm { position: static; padding-left: 40px; padding-bottom:12px;}
.dosing-twice-table figure { margin: 0 0 5px 0;}
.bronchospasm p { text-align: left;}


}


/*********Dosing page Mobile Css ends here**************/

@media only screen and (min-device-width: 768px) and (max-device-width: 1080px) and (orientation: landscape) {
    #dosing-page .dosing-video-view figure>a>img {
        min-height: 304px;
    }

    .patients-know p {
        font-size: 30px;
    }

    .inhaler-right {
        max-width: 358px;
    }
}

@media screen and (max-width: 767px) {
    #dosing-page .banner_main {
        background-position: 100% 16%;
    } 

    .patients-lists ul li p {
        font-size: 14px;
        line-height: 20px;
        gap: 20px;
    }

    .patients-lists ul li span {
        width: 52.71px;
        height: 52.71px;
        font-size: 19.76px;
    }

    .patients-lists ul li:nth-child(1) p b {
        max-width: 225px;
    }

    .patients-lists ul li:nth-child(4) b {
        max-width: 265px;
    }
    #dosing-page #moa-dosing {
        scroll-margin-top: 200px !important;
    }
    .dosing-twice-main .content-container { padding:0 5px;}
    
}

@media screen and (max-width: 667px) {
    #dosing-page .banner_main {
        background-position: 100% 20%;
    }
     
    .copd-action {
        padding: 0px 10px 0px 10px;
    }
    .dosing-twice-inner h2 { font-size: 25px;}
}

@media screen and (max-width: 537px) {
    .patients-lists p.dose-patients-daily {
        margin-bottom: 0px;
    }

    #dosing-page .sample .sample-button:last-child span {
        max-width: 235px
    }
   #dosing-page .sample-button2-order a span { padding-right: 42px; }
   
}

@media screen and (max-width: 414px) {
   

    .copd-treat-main {
        margin: 0px 15px;
    }

    .copd-treat-inner .dose-copding {
        display: block;
        color: #121312;
        font-family: 'Avenir-Medium';
        font-size: 24px;
        font-weight: 800;
        line-height: 32px;
    }

   

    .patients-know p {
        padding-top: 30px;

    }

    .dose-copding p {
        font-size: 24px;
        line-height: 32px;
    }

    .copd-treat-inner {
        padding: 20px 10px 10px 10px;

    }

    .dosing-banner-main {
        background-position: right center;
    }

    .dosing-banner-content p {
        font-size: 15px;
    }

    .patients-know {
        max-width: 285px;
    }
}

@media screen and (max-width: 335px) {
    .sample-text span {
        font-size: 16px;
    }
    #dosing-page .sample-button2-order a
    {
      padding: 17px 10px;
    }
}


#dosing-page #moa-dosing {
  scroll-margin-top: 300px;
}