#asthma-clinical-trials-data .efficacy-banner-main {
    background-image: url(/content/dam/intelligentcontent/brands/breztri-hcp/us/en/images/phase2/desktop/safety/safety_bg.jpg);
    background-size: cover;
    background-repeat: no-repeat;
    position: relative;
    min-height: 270px;
}

#asthma-clinical-trials-data .efficacy-banner {
    padding: 0;
}

#asthma-clinical-trials-data .content-container {
    max-width: 1200px;
    margin: 0 auto;
}

#asthma-clinical-trials-data .efficacy-banner-in {
    padding: 55px 0 30px 0;
}

#asthma-clinical-trials-data .efficacy-banner-content {
    padding: 0;
    max-width: 900px;
}

#asthma-clinical-trials-data .efficacy-banner-content a {
    padding: 0 0 4px 0;
    margin: 0 0 18px 0;
    border: none;
    border-bottom: 2px solid #2CD5C4;
    border-radius: 0;
    font-size: 18px;
    line-height: 24px;
    font-family: 'Avenir-Heavy';
    font-weight: 800;
    color: #FFFFFF; 
}

#asthma-clinical-trials-data .efficacy-banner-content h1 {
    font-family: 'Avenir-Black';
    color: #FFFFFF;
    font-size: 40px;
    line-height: 44px;
    font-weight: 800;
    margin: 0 0 11px 0;
}

.breztri-triple-therapy-for-astama {
    max-width: 1032px;
    margin: 0 auto;
}

#asthma-clinical-trials-data .symbi-prescribing-information {
    max-width: 1032px;
    margin: 36px auto 66px auto;
    border-radius: 18px;
    background: #E8EAE8;
    padding: 0 60px;
    text-align: center;
}

#asthma-clinical-trials-data .p-i-jump-link {
    color: #000;
    text-align: center;
    font-family: 'Gotham-Book';
    font-size: 17px;
    font-weight: 325;
    line-height: 24px;
    text-decoration-line: underline;
    text-decoration-style: solid;
}

#kalos-banner-section {
    margin-top: 60px;
}

#asthma-clinical-trials-data a.popup-therapy {
    position: absolute;
    top: -31px;
    right: -31px;
}

#asthma-clinical-trials-data a.popup-therapy img {
    width: 82px;
}

#asthma-clinical-trials-data .breztri-popup-severe figure img {
    box-shadow: rgba(0, 0, 0, 0.2) 0px 18px 50px -23px;
    border-radius: 38px;
    width: 100%;
}

.five-minutes-therapy-footnote,
.pulmonary-disease-note {
    max-width: 1030px;
    margin: 20px auto;
    padding-left: 20px;
}

.asthma-clinical-trial-data {
    max-width: 1013px;
    margin: 0 auto;
    margin-bottom: 52px;
}

.asthma-clinical-trial-data__title {
    color: black;
    font-family: 'Avenir-Black';
    font-size: 32px;
    font-weight: 900;
    line-height: 38px;
    text-transform: uppercase;
}

.asthma-clinical-trial-data__title sup {
    font-family: 'Avenir-Roman';
    font-weight: normal;
}

.breztri-logo-title {
    color: #BF890D;
    font-family: 'Avenir-Black';
    font-size: 32px;
    font-weight: 900;
    line-height: 38px;
    text-transform: uppercase;
}

.asthma-clinical-trial-data__content {
    display: flex;
    flex-wrap: wrap;
    justify-content: center;
    align-items: center;
    gap: 12px;
}

.asthma-clinical-trial-data__chart {
    max-width: 607px;
    padding-top: 41px;
    padding-bottom: 40px;
}

.asthma-clinical-trial-data__summary {
    max-width: 391px;
}

.asthma-clinical-trial-data__summary-text {
    text-align: center;
    font-family: 'Avenir-Medium';
    font-size: 24px;
    font-style: normal;
    font-weight: 500;
    line-height: 32px;
    color: #373A36;
}

.asthma-clinical-trial-data__highlighted-text {
    display: inline-block;
    color: #00A3A0;
    font-family: 'Avenir-Black';
    font-size: 28px;
    font-style: normal;
    font-weight: 900;
    line-height: 32px;
}

.asthma-clinical-trial-data__bottom-text {
    text-align: center;
    font-family: 'Avenir-Medium';
    font-size: 24px;
    font-style: normal;
    font-weight: 500;
    line-height: 32px;
    display: inline-block;
    width: 250px;
}

.asthma-clinical-trial-data__footnote {
    color: #373A36;
    font-family: 'Avenir-Book';
    font-size: 14px;
    font-weight: 350;
    line-height: 20px;
    padding-bottom: 4px;
}

.asthma-clinical-trial-data__footnotes p:first-child {
    color: #373A36;
    font-family: 'Avenir-Medium';
    font-size: 18px;
    font-style: normal;
    font-weight: 500;
    line-height: 20px;
    padding-bottom: 11px;
    padding-right: 60px;
}

#asthma-clinical-trials-data .kronos-main {
    background-color: #ffffff;
    box-shadow: 0px 4px 25px 0px #00000017;
    margin-bottom: 60px;
}

/*#asthma-clinical-trials-data .kronos-main {*/
/*    background-color: #ffffff;*/
/*    box-shadow: 0px 4px 25px 0px #00000017;*/
/*    margin-bottom: 55px;*/
/*}*/

#asthma-clinical-trials-data .kronos-data {
    padding: 32px 45px;
    max-width: 980px;
    padding-bottom: 20px;
}

#asthma-clinical-trials-data .kronos-data h3 {
    font-family: 'Avenir-Heavy';
    font-size: 20px;
    line-height: 32px;
    font-weight: 800;
    color: #121312;
    margin: 0 0 12px 0;
}

#asthma-clinical-trials-data .kronos-data p {
    font-size: 16px;
    line-height: 24px;
    padding-bottom: 12px;
}

#asthma-clinical-trials-data .breztri-prescribing-information a {
    text-decoration: underline;
    color: #000000;
}

#asthma-clinical-trials-data .breztri-prescribing-information {
    text-align: center;
}

#asthma-clinical-trials-data .demonstrate-main {
    padding: 22px 0 40px 0;
}

#asthma-clinical-trials-data .clinical-data-container {
    max-width: 1025px;
    padding: 0 15px;
    margin: 0 auto;
}

#asthma-clinical-trials-data .demonstrate-head h3 {
    font-family: 'Avenir-Black';
    font-size: 39px;
    line-height: 42px;
    color: #373A36;
    font-weight: 900;
    text-align: center;
    text-transform: uppercase;
}

#asthma-clinical-trials-data .clinical-data-container {
    max-width: 1025px;
    padding: 0 15px;
    margin: 0 auto;
}

#asthma-clinical-trials-data .sample-button-block {
    display: flex;
    align-items: center;
    justify-content: center;
    padding: 55px 0 15px 0;
}

#asthma-clinical-trials-data .sample-button-order {
    margin-right: 20px;
}

#asthma-clinical-trials-data .sample-button2-order {
    margin-right: 0;
}

#clinical-pi-jump-link-section .kronos-main {
    background-color: #E8EAE8;
    box-shadow: 0px 4px 25px 0px #00000017;
    margin-bottom: 55px;
}

#asthma-clinical-trials-data .clinical-pi-jump-link-section .kronos-main {
    background-color: #E8EAE8;
    box-shadow: 0px 4px 25px 0px #00000017;
    margin-bottom: 33px;
}

#asthma-clinical-trials-data .clinical-pi-jump-link-section .kronos-data {
    padding: 24px 12px;
}

#asthma-clinical-trials-data .clinical-pi-jump-link-section a p {
    color: #000;
    text-align: center;
    font-family: 'Gotham-Book';
    font-size: 17px;
    font-style: normal;
    font-weight: 325;
    line-height: 24px;
}

#asthma-clinical-trials-data .clinical-pi-jump-link-section a p span {
    text-decoration: underline;
}

#asthma-clinical-trials-data .clinical-data-container {
    max-width: 1032px;
    margin: 0 auto;
    /* padding: 0; */
}

.breztri-triple-therapy-for-astama figure {
    margin: 0;
}

.asthma-clinical-trial-data__top-text {
    display: inline-block;
    width: 320px;
}

/* model popup-isi starts here*/

body .popup-clinical-isi.modal.cmp-modal__modalbox .modal__closeIcon {
    z-index: 99;
}

span.modal__closeIcon {
    pointer-events: auto;
}

body.modal-enabled {
    overflow-y: hidden;
    width: 100%;
    height: 100vh;
    position: fixed;
    z-index: 999999;
}

body .popup-clinical-isi.modal.cmp-modal--defaultStyle.modal--visible {
    padding-top: 2vh;
    padding-bottom: 10vh;
}

body .popup-clinical-isi.modal.cmp-modal__modalbox {
    position: fixed;
    top: 0;
    right: 0;
    bottom: 0;
    left: 0;
    z-index: 1000;
    background: rgba(0, 0, 0, 0.7);
    backdrop-filter: none;
    -webkit-backdrop-filter: none;
    cursor: auto;
}

body .popup-clinical-isi.modal.cmp-modal__modalbox .modal__close {
    color: #455E89;
    display: flex;
    flex-direction: row-reverse;
    justify-content: end;
    position: relative;
    width: 100%;
    cursor: auto;
    top: 0;
    left: 0;
    margin: 0 auto;
    max-width: 1340px;
    z-index: 999;
    padding: 0;
    padding-right: 0;
    height: 50px;
    outline: none;
    pointer-events: none;
    margin-bottom: 0;
}

body .popup-clinical-isi.modal.cmp-modal__modalbox .modal__close svg {
    background-image: url(/content/dam/intelligentcontent/brands/breztri-hcp/us/en/images/phase2/desktop/efficacy/close_icon.svg);
    background-repeat: no-repeat;
    padding: 10px;
    border-radius: 100%;
    width: 86px;
    height: 86px;
    border: 0px solid #fff;
    color: #fff;
    background-size: 86px;
}

body .popup-clinical-isi.modal.cmp-modal__modalbox .modal-box {
    max-width: 1172px;
    margin: 0 auto;
    background: #ffffff;
    border-radius: 16px;
    padding: 0;
    position: relative;
    top: 30px;
    animation: none;
    width: 95%;
}

body .popup-clinical-isi.cmp-modal--defaultStyle .modal__close svg * {
    fill: transparent;
}

body .popup-clinical-isi.modal.cmp-modal__modalbox .modal-box .modal-box__content {
    padding: 0;
}

body .popup-clinical-isi.cmp-modal__content {
    padding: 0 25px;
}

body .popup-clinical-isi.cmp-video__player {
    padding: 0 15px;
}

/* model popup-isi ends here*/

.asthma-imp {
    padding: 0;
}

.asthma-imp h2 {
    font-size: 31px;
    font-family: 'Avenir-Black';
    font-weight: 900;
    line-height: 34px;
    color: #373A36;
    margin: 0 0 20px 0;
    padding-right: 50px;
    max-width: 1007px;
    text-transform: uppercase;
}

.asthma-clinical-isi-container {
    padding: 10px 40px 55px 40px;
}

.asthma-clinical-isi-content {
    padding: 0;
}

.asthma-clinical-isi ul li {
    position: relative;
    padding-left: 14px;
    margin: 0 0 16px 0;
}

.asthma-clinical-isi ul li::before {
    content: '';
    position: absolute;
    left: 0;
    top: 8px;
    width: 6px;
    height: 6px;
    border-radius: 100%;
    background-color: #121312;
}

.asthma-clinical-isi ul li p {
    font-family: 'Avenir-Book';
    font-size: 16px;
    line-height: 24px;
    color: #121312;
    font-weight: 400;
}

.clinical-approve h3 {
    font-size: 18px;
    line-height: 20px;
    color: #121312;
    margin: 0 0 12px 0;
    font-family: 'Avenir-Heavy';
    font-weight: 800;
}

.clinical-approve p {
    font-family: 'Avenir-Book';
    font-size: 16px;
    line-height: 24px;
    color: #121312;
    font-weight: 400;
    padding: 0 0 12px 0;
}

.clinical-approve p span {
    font-weight: 700;
}

.clinical-approve {
    padding: 10px 0 10px 0;
}

.symbicourt p {
    font-size: 16px;
    line-height: 24px;
    color: #121312;
    font-family: 'Avenir-Heavy';
    font-weight: 800;
}

.symbicourt p a {
    color: #232DF0;
    text-decoration: underline;
}
.clinical-popup-report 
{
  padding: 20px 0 0 0;
}
.clinical-popup-report p 
{
   font-family: 'Avenir-Book';
    font-size: 16px;
    line-height: 24px;
    color: #121312;  
}
.clinical-popup-report p a
{
   font-family: 'Avenir-Heavy';
   font-weight: 800; color: #232DF0;
}
.clinical-popup-report p a { text-decoration: underline;} 
.clinical-popup-report p a.clinical-report-link i.fa-external-link {
    position: relative;
   top: 1px;
    padding-left: 5px;
    font-size: 14px;
}
 
@media screen and (min-width: 991px) {
    .breztri-triple-therapy-for-astama figure img {
        min-width: 1032px;
    }

    #asthma-clinical-trials-data .clinical-pi-jump-link-section .kronos-main {
        background-color: #E8EAE8;
        box-shadow: 0px 4px 25px 0px #00000017;
        margin-bottom: 38px;
        margin-top: 30px;
    }

    .clinical-data-container-text {
        margin: 0 auto;
        max-width: 1032px;
    }

    #asthma-clinical-trials-data .clinical-pi-jump-link-section .kronos-data {
        padding: 6px 12px;
    }

    .asthma-clinical-trial-data__title {
        color: black;
        font-family: 'Avenir-Black';
        font-size: 32px;
        font-weight: 900;
        line-height: 38px;
        text-transform: uppercase;
        padding-right: 160px;
    }

    .newly-added-content {
        text-align: left;
        max-width: 980px;
        margin: 0 auto;
        margin-bottom: 48px;
        padding-left: 25px;
    }

    .newly-added-content p {
        padding-left: 6px;
        font-size: 13px;
    }
}

@media screen and (max-width: 991px) {
    .asthma-clinical-trial-data {
        padding: 0 16px;
    }

    .symbi-prescribing-information {
        margin: 0 16px;
        padding: 24px 12px;
    }

    .asthma-clinical-trial-data__footnote {
        padding-bottom: 4px;
    }

    .asthma-clinical-trial-data__footnotes p:first-child {
        padding-top: 26px;
        padding-bottom: 23px;
    }

    #asthma-clinical-trials-data .content-container {
        padding-left: 15px;
        padding-right: 15px;
    }

    #asthma-clinical-trials-data .sample-button-block {
        display: block;
        text-align: center;
    }

    #asthma-clinical-trials-data .sample-button-block {
        padding: 30px 0 50px 0;
    }

    #asthma-clinical-trials-data .sample-button-order {
        margin-bottom: 20px;
        margin-right: 0;
    }

    #asthma-clinical-trials-data .sample-button2-order {
        margin-bottom: 0;
    }

    #asthma-clinical-trials-data .efficacy-banner-content h1 {
        color: #FFFFFF;
        font-family: 'Avenir-Black';
        font-size: 29px;
        font-style: normal;
        font-weight: 900;
        line-height: 33px;
    }

    #asthma-clinical-trials-data .efficacy-banner-content a {
        color: white;
        font-family: 'Avenir-Heavy';
        font-size: 18px;
        font-style: normal;
        font-weight: 800;
        line-height: 24px;
    }

    #kalos-banner-section {
        margin-top: 35px;
    }

    #asthma-clinical-trials-data .kronos-data {
        padding: 24px;
        padding-bottom: 12px;
    }

    #asthma-clinical-trials-data .kronos-data h3 {
        color: #121312;
        font-family: 'Avenir-Roman';
        font-size: 17px;
        font-style: normal;
        font-weight: 800;
        line-height: 120%;
    }

    .breztri-clinical-results-section__description {
        color: #121312;
        font-family: 'Avenir-Book';
        font-size: 16px;
        font-weight: 350;
        line-height: 24px;
        padding-bottom: 12px;
    }

    #asthma-clinical-trials-data .clinical-pi-jump-link-section .kronos-main {
        background-color: #E8EAE8;
        box-shadow: 0px 4px 25px 0px #00000017;
        margin-bottom: 33px;
        margin-top: 24px;
    }

    #triple-therapy-for-astama {
        padding: 0 16px;
    }

    #asthma-clinical-trials-data .clinical-pi-jump-link-section .kronos-data {
        padding: 24px 12px;
    }

    #asthma-clinical-trials-data a.popup-therapy {
        position: absolute;
        top: -30px;
        right: -15px;
    }

    #asthma-clinical-trials-data .clinical-pi-jump-link-section a p {
        color: #000;
        text-align: center;
        font-family: 'Gotham-Book';
        font-size: 17px;
        font-style: normal;
        font-weight: 325;
        line-height: 24px;
        /*text-decoration-line: underline;*/
        margin: 0 10px;
    }

    a.popup-therapy img {
        max-width: 74px;
    }

    #asthma-clinical-trials-data .demonstrate-head h3 {
        color: #373A36;
        text-align: center;
        font-family: 'Avenir-Heavy';
        font-size: 26px;
        font-style: normal;
        font-weight: 900;
        line-height: 30px;
        text-transform: uppercase;
        padding: 0 7px;
    }

    #asthma-clinical-trials-data .pulmonary-disease-note {
        padding-left: 0;
    }

    #asthma-clinical-trials-data .pulmonary-disease-note p {
        color: #000;
        font-family: 'Avenir-Book';
        font-size: 12px;
        font-style: normal;
        font-weight: 350;
        line-height: 120%;
        padding: 0 45px;
    }

    #asthma-clinical-trials-data .five-minutes-therapy-footnote {
        padding: 0 16px;
    }

    #asthma-clinical-trials-data .kronos-main {
        background-color: #ffffff;
        box-shadow: 0px 4px 25px 0px #00000017;
        margin-bottom: 48px;
    }

    .newly-added-content {
        text-align: left;
        margin-bottom: 38px;
        padding-left: 11px;
    }

    #asthma-clinical-trials-data #isi-safety-info {
        background: #F0B323;
        padding-bottom: 10px;
        padding-top: 10px;
        margin-top: 10px;
        margin-bottom: 5px;
    }

    .newly-added-content p {
        padding-left: 7px;
        font-size: 12px;
        position: relative;
        line-height: 14px;
        left: 6px;
        padding-right: 20px;
    }

    .newly-added-content p span {
        position: absolute;
        left: 0;
    }

    .breztri-triple-therapy-for-astama {
        max-width: 1032px;
        margin: 0 auto;
        text-align: center;
    }

    #asthma-clinical-trials-data .reference-content ul li:last-child {
        margin-bottom: 0;
        padding-right: 19px;
    }

    #asthma-clinical-trials-data .clinical-pi-jump-link-section .kronos-data {
        padding: 24px 5px;
    }

    .asthma-clinical-trial-data__footnotes .asthma-clinical-trial-data__footnote:nth-last-child(3) {
        text-indent: -8px;
        padding-left: 8px;
    }

    .asthma-clinical-trial-data__title {
        font-size: 23px;
        line-height: 32px;
        padding-right: 50px;
    }

    .breztri-logo-title {
        font-size: 23px;
        line-height: 32px;
    }

    .asthma-clinical-trial-data__summary-text {
        font-size: 20px;
        line-height: 28px;
        width: 100%;
        padding: 0 20px;
    }

    .asthma-clinical-trial-data__highlighted-text {
        font-size: 24px;
        line-height: 28px;
    }

    .asthma-clinical-trial-data__bottom-text {
        font-size: 20px;
        line-height: 28px;
        width: 200px;
    }

    .asthma-clinical-trial-data__footnotes p:first-child {
        padding-right: 0;
    }

    #asthma-clinical-trials-data .breztri-popup-severe figure img {
        border-radius: 41px;
    }

    .asthma-clinical-trial-data {
        margin-bottom: 30px;
    }

    #asthma-clinical-trials-data .kronos-data p {
        padding-bottom: 0;
    }

    body .popup-clinical-isi.modal.cmp-modal__modalbox .modal__close {
        background: transparent;
    }

    body .popup-clinical-isi.modal.cmp-modal__modalbox .modal__closeIcon {
        width: auto;
        margin-right: 0;
    }

    .asthma-clinical-isi-container {
        padding: 0 12px; padding-bottom: 45px;
    }

    .asthma-imp h2 {
       font-size: 23px;
        line-height: 26px;
        margin: 0 0 18px 0; 
    }
    
  
    body .popup-clinical-isi.cmp-modal--defaultStyle .modal__closeLabel {
        display: none;
    }

    .asthma-clinical-isi-sub {
        margin-left: 20px;
    }
    body .popup-clinical-isi.modal.cmp-modal__modalbox .modal__close svg
    {
        width: 65px;
        height: 65px;
        background-size: 65px;
    }
    body .popup-clinical-isi.modal.cmp-modal__modalbox .modal-box
    {
      width: 90%;
    }
    .asthma-imp { margin-top: -16px;}
    .clinical-approve { padding: 10px 0 6px 0;}
}

@media screen and (max-width: 767px) {}

@media screen and (max-width: 667px) {
    .asthma-clinical-trial-data__title {
        padding-right: 0;
    }

    .breztri-logo-title {
        display: block;
    }
    .asthma-imp h2 span { display: block;}
    .asthma-imp h2 { padding-right: 0;}
    .symbicourt { max-width: 360px;}
}

@media screen and (max-width: 475px) {

    .asthma-clinical-trial-data__top-text {
        width: auto;
    }
}

.asthma-clinical-trial-data__footnotes .asthma-clinical-trial-data__footnote:nth-last-child(2) {
    text-indent: -6px;
    padding-left: 5px;
}

.asthma-clinical-trial-data__footnotes .asthma-clinical-trial-data__footnote:last-child {
    font-size: 13px;
}

.pulmonary-disease-note-content-update {
    padding-bottom: 8px;
}